Tag Archives: drug

Critical new allergy pathway: Mouse study discovery points to potential new drug targets for treating asthma, hay fever, and other inflammatory disorders – Science Daily

Researchers at Johns Hopkins Bloomberg School of Public Health have identified the sequence of molecular events by which tiny, tick-like creatures called house dust mites trigger asthma and allergic rhinitis. The researchers, whose study was published online June 22 in Nature Immunology, found that allergy-triggering molecules from dust mites can interact with an immune protein… Read More »

Blood pressure drug improves response to cancer therapy

Scientists at Heidelberg University Hospital and the European Molecular Biology Laboratory (EMBL) have discovered that a drug to lower blood pressure alters the tissue characteristics of secondary tumours, or metastases, from colon cancer. The ‘stiffness’ of these metastases has an effect on the success of cancer therapies. The results are published in Cancer Cell. Heidelberg… Read More »

Brain tumors respond well to combo of radiation, schizophrenia drug

By Denise Heady Researchers at the UCLA Jonsson Comprehensive Cancer Center and colleagues have found that adding a drug once commonly used to treat schizophrenia to traditional radiation therapy helped improve overall survival in mice with glioblastoma, one of the deadliest and most difficult-to-treat brain tumors. The findings, published May 1 in Proceedings of the National Academy of Sciences,… Read More »

Drug shows promise in reversing kidney damage caused by lupus

By Bill Hathaway A drug used for cancer therapy has shown promise in reversing kidney damage caused by systemic lupus erythematosus (SLE, or lupus), according to a Yale-led study published April 8 in the journal Science Translational Medicine. “Kidney damage affects about half of the patients with lupus, sometimes leading to renal failure with a requirement… Read More »

Canadian prescriptions for malaria drug with COVID-19 potential surge, some for doctors’ own use

Some Canadian doctors appear to have been snapping up a malaria drug for their own possible use against COVID-19, part of a surge in prescriptions for the medicine that has health-care regulators across the country concerned. Professional organizations in several provinces have issued statements in recent days discouraging the practice, noting there’s no solid evidence… Read More »

COVID-19 is bad news for new drug launches. Which will suffer most?

The COVID-19 pandemic and the ensuing societal countermeasures are upending operations in many sectors—and biopharma isn’t immune. The current lockdown is not only hurting clinical trial enrollment but also delaying regulatory timelines for drugs nearing a decision. And with tried-and-true, in-person marketing techniques no longer allowed, new launches may also feel the pain—or hold off altogether. Consider Bristol… Read More »